The changing circumstance of atrial fibrillation - progress towards precision medicine

Towards Cardio-Precision medicine.

Genomic medicine and atrial fibrillation.

Recent developments and improved understanding in genomics (the interactions and functions of genes) have profoundly changed the perspective of researchers and medical practitioners toward diseases that had previously been associated with environmental factors alone (1). It is now widely recognized that many common disorders, such as heart disease, cancer, infections, Parkinson’s disease, and A...

Progress towards personalized medicine.

Personalized medicine is the tailoring of therapies to defined subsets of patients based on their likelihood to respond to therapy or their risk of adverse events. The advent of improved genomic tools has greatly hastened our understanding of the molecular pathology of diseases, enabling us to redefine disease at the molecular level. The development of molecularly targeted therapies, coupled wi...

Intravenous Methylprednisolone, a Possible Cause of the Atrial Fibrillation

       We are presenting a case illustrating atrial fibrillation (AF) following the use of methylprednisolone in a patient with pelvic and femur fracture. A 48- year- old man with no significant past medical history, was admitted to the emergency department after injury in a car accident. He suffered a multiple bone fracture with chief complaints of pain and shortness of breath. He was transfer...

Towards precision medicine: The application of omics

Asthma is a chronic obstructive respiratory disease characterised by bronchial inflammation. Its biological and clinical features have been widely explored and a number of pharmacological treatments are currently available. Currently several aspects of asthma pathophysiological background remain unclear, and this is crucial for the traditional asthma phenotype approach as well as for new endoty...